Tirzepatide (mounjaro) 5mg 10mg 15mg ente

tlhaloso e khuts'oane:

Lebitso: Tirzepatide

Lintlha: 5mg/vial*10vials/box 10mg/vial*10vial/box 15mg/vial*10vial/box

Theko: 5mg USD110/box 10mg USD220/box 15mg USD330/box

Lab: Lianfu Bio

MOQ: 1 lebokose

Re romelle lengolo-tsoibila

Lintlha tsa Sehlahisoa

Tirzepatide

Tirzepatide ke lipatlisiso hanngoe ka beke, insulinotropic polypeptide e itšetlehileng ka tsoekere e habeli le glucagon-like peptide-1 receptor agonist e kopanyang liketso tsa li-incretin ka bobeli ho molek'hule e le 'ngoe.

Tirzepatide Mimics Li-Hormone tsa Tlhaho tse Kholisang Boikutlo bo Felletseng
Tirzepatide e sebetsa ka ho etsisa lihomone tsa GLP-1 le GIP tseo ka tlhaho li hlahisoang ke mala ka mor'a lijo, e leng se susumetsang tlhahiso ea insulin.E boetse e fokotsa takatso ea lijo ka ho liehisa nako eo e nkang mpa hore e tsoe le ho sebelisana le libaka tse bokong tse nang le li-receptor tsa GLP-1 ho bonts'a ho khora.

Tirzepatide ke moriana o mocha o lumelletsoeng ke FDA bakeng sa kalafo ea lefu la tsoekere la mofuta oa 2.Ka lebaka la litšobotsi tsa eona tse matla tsa ho theola boima ba 'mele,tirzepatidee sebedise kantle ho label bakeng sa kalafo ya botenya.E sebetsa e le agonist ea GLP-1 le GIP agonist ho eketsa melemo e ts'oanang e bonoang ka meriana ea GLP-1 joalo ka semaglutide.Hajoale e sebelisoa e le moriana oa lefu la tsoekere oa mofuta oa bobeli, o ts'oanang le oa GLP-1, 'me o fanoa e le ente e kenang hanngoe ka beke ea subcutaneous.

Tirzepatide ke receptor e itšetlehileng ka tsoekere ea insulinotropic polypeptide (GIP) le glucagon-like peptide-1 (GLP-1) recepto agonist, e amohetsoeng ke FDA bakeng sa ho alafa lefu la tsoekere la mofuta oa 2.Ho bohlokoa ho hlokomela hore tirzepatide ha e lumelloe ho phekola lefu la tsoekere la mofuta oa 1 mme ha e so ithutoe ho bakuli ba nang le pancreatitis.Tirzepatide ke GIP receptor le GLP-1 receptor agonist, e lebisang ho ntlafatseng taolo ea glycemic ho bakuli ba lefu la tsoekere la mofuta oa 2 le phokotso e kholo ea boima ba 'mele.

FDA e amohetse Tirzepatide ka Mots'eanong 2022. Tirzepatide e ka boela ea sebelisoa kantle ho label bakeng sa ho alafa botenya.Hajoale e sebelisoa e le moriana oa lefu la tsoekere oa mofuta oa bobeli, o ts'oanang le meriana ea GLP-1 joalo ka semaglutide.Ke moriana o kenang hanngoe ka beke o kenang ka tlas'a letlalo o nang le keketseho ea lethal dose.

Lintlha tsa morao-rao tsa kliniki li bontšitse hore tirzepatide e phahametse placebo ho ntlafatsa maemo a hemoglobin A1C.Teko ea kliniki ea SURPASS-5 e bontšitse ho fokotseha ha -2.11% maemong a hemoglobin A1C ho 5mg ka beke dosing, ha ho bapisoa le -0.86% le placebo.Ka tekanyo e phahameng ka ho fetisisa ea 15 mg ka beke, tirzepatide e lebisitse ho fokotseha ha -2.34% ho hemoglobin A1C.Sena se ile sa bontšoa ka libeke tse 40.Phokotso ea boima ba 5.4 kg e ile ea bonoa ka 5mg ea dosing ea tirzepatide, mme phokotso ea 10.5 kg e ile ea bonoa ka 15 mg dosing.Kamano ena e itšetlehileng ka tekanyo ea tekanyo le tahlehelo ea boima ba 'mele e tšoana le semaglutide, meriana e tloaelehileng ea GLP-1 e sebelisetsoang ho laola boima ba' mele.

Ha ho bapisoa, ho bontšitsoe hore tirzepatide e sebetsa ka mokhoa o ts'oanang le meriana ea GLP-1 empa ka katleho e kholo.Ka lebaka la thepa ea eona ea ho theola boima ba 'mele le ho hloka chefo ea sebete, ho ka etsahala hore e be le karolo e sa tobang ho phekola lefu la sebete le se nang joala le mafura (NAFLD) hape.