SR9009 lipilisi 100 matlapa/botlolo

Lebitso la Sehlahiswa:SR9009

Spacification: 10 mg/pilisi 100 lipilisi/botlolo

Theko: $80/botlolo

MOQ: botlolo ea 1

Lab: LianFu Bio

Tlhaloso ea lihlahisoa

SR9009, e REV-ERBagonist, e eketsa khatello ea maikutlo ea liphatsa tsa lefutso tse laoloang ke REV-ERBα / ERBβ (IC50: 670 / 800 nM).Ka ts'ebetso ea REV-ERB, SR9009 e ka fokotsa ts'ebetso ea circadian locomotor nakong ea lefifi mme ea fetola sebopeho sa polelo ea liphatsa tsa lefutso tsa mantlha hypothalami ea litoeba.Sebopeho sa circadian sa polelo ea mefuta e mengata ea liphatsa tsa lefutso sebeteng, mesifa ea marapo le adipose le eona e ile ea fetoloa ho litoeba tse pepeselitsoeng SR9009, e leng se ileng sa fella ka ho eketseha ha tšebeliso ea matla.

SR9009 (100 mg/kg, ip, bid, bakeng sa matsatsi a 30) e ka khonafokotsa boima ba mafurale ka mokhoa o hlokomelehangntlafatsa dyslipidemialehyperglycemia.